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Afsaneh Nikjooy

Iran University of Medical Sciences, Iran

Title: Accurate differentiation of dyssynergic defecation patients from normal subjects based on abnormal anorectal angle in MR Defecography

Biography

Biography: Afsaneh Nikjooy

Abstract

We aimed to study the differences between the dynamic indices of the pelvic floor, i.e. anorectal angle and perineal descent, in dyssynergic defecation patients in comparison with healthy controls, based on MR Defecography. 22 constipated patients with dyssynergic defecation and 14 healthy asymptomatic subjects were included in the study. 4 MR Defecography dynamic indices, including paradox (abnormal anorectal angle change), perineal descent during straining, perineal ascent, and narrowing of anorectal angle at squeeze, were measured in patients and healthy subjects. Paradox Index had the highest sensitivity (95.45%) and specificity (92.86%) for detection of dyssynergic defecation, with an R2 value of near 1 (0.902). The sensitivity and specificity of other indices were not high; therefore, no significant improvement could be achieved using other indices along with Paradox Index. Negative Predictive Value (92.85%) and Positive Predictive Value (95.45%) were only high in Paradox Index. Paradox Index was indicated to be the best finding of MR Defecography for identifying dyssynergic defecation patients from healthy controls. Hence, MR Defecography could be exploited as a reliable tool to show the patients the paradoxical function of their pelvic floor muscles, which could enhance their imagination of the correct defecation pattern during their therapy.